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Aldehyde dehydrogenase 1A1 and 1A3 isoforms – mechanism of activation and regulation in cancer()

In some types of human cancer, aldehyde dehydrogenases represent stemness markers and their expression is associated with advanced disease stages and poor prognosis. Although several biological functions are mediated by their product Retinoid acid, the molecular mechanism is tissue-dependent and onl...

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Detalles Bibliográficos
Autores principales: Poturnajova, M., Kozovska, Z., Matuskova, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505796/
https://www.ncbi.nlm.nih.gov/pubmed/34428540
http://dx.doi.org/10.1016/j.cellsig.2021.110120