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Myeloid malignancies with translocation t(4;12)(q11‐13;p13): molecular landscape, clonal hierarchy and clinical outcomes

Translocation t(4;12)(q11‐13;p13) is a recurrent but very rare chromosomal aberration in acute myeloid leukaemia (AML) resulting in the non‐constant expression of a CHIC2/ETV6 fusion transcript. We report clinico‐biological features, molecular characteristics and outcomes of 21 cases of t(4;12) incl...

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Detalles Bibliográficos
Autores principales: Parinet, Vincent, Chapiro, Elise, Bidet, Audrey, Gaillard, Baptiste, Maarek, Odile, Simon, Laurence, Lefebvre, Christine, Defasque, Sabine, Mozziconacci, Marie‐Joelle, Quinquenel, Anne, Decamp, Matthieu, Lifermann, François, Ali‐Ammar, Nadia, Maillon, Agathe, Baron, Marine, Martin, Mélanie, Struski, Stéphanie, Penther, Dominique, Micol, Jean‐Baptiste, Auger, Nathalie, Bilhou‐Nabera, Chrystèle, Martignoles, Jean‐Alain, Tondeur, Sylvie, Nguyen‐Khac, Florence, Hirsch, Pierre, Roos‐Weil, Damien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505829/
https://www.ncbi.nlm.nih.gov/pubmed/34492730
http://dx.doi.org/10.1111/jcmm.16895