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Hypoxia‐inducible factor 1‐alpha acts as a bridge factor for crosstalk between ERK1/2 and caspases in hypoxia‐induced apoptosis of cementoblasts

Hypoxia‐induced apoptosis of cementoblasts (OCCM‐30) may be harmful to orthodontic treatment. Hypoxia‐inducible factor 1‐alpha (HIF‐1α) mediates the biological effects during hypoxia. Little is known about the survival mechanism capable to counteract cementoblast apoptosis. We aimed to investigate t...

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Detalles Bibliográficos
Autores principales: Yong, Jiawen, von Bremen, Julia, Groeger, Sabine, Ruiz‐Heiland, Gisela, Ruf, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505834/
https://www.ncbi.nlm.nih.gov/pubmed/34523215
http://dx.doi.org/10.1111/jcmm.16920