Prolyl oligopeptidase inhibition reduces alpha‐synuclein aggregation in a cellular model of multiple system atrophy

Multiple system atrophy (MSA) is a fatal neurodegenerative disease where the histopathological hallmark is glial cytoplasmic inclusions in oligodendrocytes, rich of aggregated alpha‐synuclein (aSyn). Therefore, therapies targeting aSyn aggregation and toxicity have been studied as a possible disease...

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Detalles Bibliográficos
Autores principales: Cui, Hengjing, Kilpeläinen, Tommi, Zouzoula, Lydia, Auno, Samuli, Trontti, Kalevi, Kurvonen, Sampo, Norrbacka, Susanna, Hovatta, Iiris, Jensen, Poul Henning, Myöhänen, Timo T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505845/
https://www.ncbi.nlm.nih.gov/pubmed/34486218
http://dx.doi.org/10.1111/jcmm.16910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505845/
https://www.ncbi.nlm.nih.gov/pubmed/34486218
http://dx.doi.org/10.1111/jcmm.16910

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