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Knockdown of miR‐423‐5p simultaneously upgrades the eNOS and VEGFa pathways in ADSCs and improves erectile function in diabetic rats

This study aimed to explore the possibility of miR‐423‐5p modified adipose‐derived stem cell (ADSCs) therapy on streptozotocin (STZ)‐induced diabetes mellitus erectile dysfunction (DMED) rats. MiR‐423‐5p was knocked down in ADSCs. ADSCs, NC‐miR‐ADSCs and miR‐ADSCs were co‐cultured with human umbilic...

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Detalles Bibliográficos
Autores principales: Zhou, Jun, Yin, Yinghao, Yang, Yuan, Peng, Dongyi, Wei, Jingchao, Yin, Guangming, Tang, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505849/
https://www.ncbi.nlm.nih.gov/pubmed/34545676
http://dx.doi.org/10.1111/jcmm.16927