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Breakage of CRISPR/Cas9-Induced Chromosome Bridges in Mitotic Cells

Chromosomal instability, the most frequent form of plasticity in cancer cells, often proceeds through the formation of chromosome bridges. Despite the importance of these bridges in tumor initiation and progression, debate remains over how and when they are resolved. In this study, we investigated t...

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Detalles Bibliográficos
Autores principales: Rodriguez-Muñoz, Marina, Serrat, Martina, Soler, David, Genescà, Anna, Anglada, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505897/
https://www.ncbi.nlm.nih.gov/pubmed/34650988
http://dx.doi.org/10.3389/fcell.2021.745195