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Breakage of CRISPR/Cas9-Induced Chromosome Bridges in Mitotic Cells
Chromosomal instability, the most frequent form of plasticity in cancer cells, often proceeds through the formation of chromosome bridges. Despite the importance of these bridges in tumor initiation and progression, debate remains over how and when they are resolved. In this study, we investigated t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505897/ https://www.ncbi.nlm.nih.gov/pubmed/34650988 http://dx.doi.org/10.3389/fcell.2021.745195 |