Safety of a Novel Listeria monocytogenes-Based Vaccine Vector Expressing NcSAG1 (Neospora caninum Surface Antigen 1)

Listeria monocytogenes (LM) has been proposed as vaccine vector in various cancers and infectious diseases since LM induces a strong immune response. In this study, we developed a novel and safe LM-based vaccine vector platform, by engineering a triple attenuated mutant (Lm3Dx) (ΔactA, ΔinlA, ΔinlB)...

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Detalles Bibliográficos
Autores principales: Pownall, William Robert, Imhof, Dennis, Trigo, Nerea Fernandez, Ganal-Vonarburg, Stephanie C., Plattet, Philippe, Monney, Camille, Forterre, Franck, Hemphill, Andrew, Oevermann, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506043/
https://www.ncbi.nlm.nih.gov/pubmed/34650932
http://dx.doi.org/10.3389/fcimb.2021.675219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506043/
https://www.ncbi.nlm.nih.gov/pubmed/34650932
http://dx.doi.org/10.3389/fcimb.2021.675219

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