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Safety of a Novel Listeria monocytogenes-Based Vaccine Vector Expressing NcSAG1 (Neospora caninum Surface Antigen 1)
Listeria monocytogenes (LM) has been proposed as vaccine vector in various cancers and infectious diseases since LM induces a strong immune response. In this study, we developed a novel and safe LM-based vaccine vector platform, by engineering a triple attenuated mutant (Lm3Dx) (ΔactA, ΔinlA, ΔinlB)...
Autores principales: | Pownall, William Robert, Imhof, Dennis, Trigo, Nerea Fernandez, Ganal-Vonarburg, Stephanie C., Plattet, Philippe, Monney, Camille, Forterre, Franck, Hemphill, Andrew, Oevermann, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506043/ https://www.ncbi.nlm.nih.gov/pubmed/34650932 http://dx.doi.org/10.3389/fcimb.2021.675219 |
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