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Natural biflavones are potent inhibitors against SARS-CoV-2 papain-like protease

Papain-like protease (PL(pro)) is a key enzyme encoded by SARS-CoV-2 that is essential for viral replication and immune evasion. Significant suppression of viral spread and promotion of antiviral immunity can be achieved by inhibition of PL(pro), revealing an inspiring strategy for COVID-19 treatmen...

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Detalles Bibliográficos
Autores principales: Li, Lingyu, Ma, Liyan, Hu, Yue, Li, Xiaoxue, Yu, Meng, Shang, Hai, Zou, Zhongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506144/
https://www.ncbi.nlm.nih.gov/pubmed/34757253
http://dx.doi.org/10.1016/j.phytochem.2021.112984