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Hypoxia-preconditioned mesenchymal stem cells attenuate microglial pyroptosis after intracerebral hemorrhage

BACKGROUND: Microglia plays a vital role in neuroinflammation, contributing to the pathogenesis of intracerebral hemorrhage (ICH)-induced brain injury. Mesenchymal stem cells (MSCs) hold great potential for treating ICH. We previously revealed that MSCs ameliorate the microglial pyroptosis caused by...

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Detalles Bibliográficos
Autores principales: Liu, Jianyang, He, Jialin, Huang, Yan, Ge, Lite, Xiao, Han, Zeng, Liuwang, Jiang, Zheng, Lu, Ming, Hu, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506532/
https://www.ncbi.nlm.nih.gov/pubmed/34733914
http://dx.doi.org/10.21037/atm-21-2590