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Triptolide inhibits neutrophil extracellular trap formation

BACKGROUND: Triptolide (PG490), as a triterpene dicyclic oxide has been reported to increase the generation of reactive oxygen species (ROS) and nitric oxide (NO) and induce apoptosis of RAW 264.7 cells in a dose-dependent manner. The activity of death NETs plays an important role in anti-bacterial...

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Detalles Bibliográficos
Autores principales: Guan, Haiyu, Xie, Lifen, Ji, Zhenzhen, Song, Rui, Qi, Jieying, Nie, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506553/
https://www.ncbi.nlm.nih.gov/pubmed/34733936
http://dx.doi.org/10.21037/atm-21-3522