TNF-α-stimulated nucleus pulposus cells induce cell apoptosis through the release of exosomal miR-16 targeting IGF-1 and IGF-1R in rats

BACKGROUND: Exosomes may contain excess cellular components released by cells in response to harmful external stimuli to maintain cellular homeostasis. Inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-α), can induce cell apoptosis, alter cellular component expression levels, and stim...

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Detalles Bibliográficos
Autores principales: Zhang, Qi-Chen, Zou, Yan-Pei, Hu, Shun-Qi, Zhang, Tai-Wei, Zhou, Hao, Liang, Bing, Zhuang, Chen-Yang, Wang, Hui-Ren, Jiang, Li-Bo, Li, Xi-Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506555/
https://www.ncbi.nlm.nih.gov/pubmed/34733928
http://dx.doi.org/10.21037/atm-21-227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506555/
https://www.ncbi.nlm.nih.gov/pubmed/34733928
http://dx.doi.org/10.21037/atm-21-227

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