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Phosphoproteomics identifies potential downstream targets of the integrin α2β1 inhibitor BTT-3033 in prostate stromal cells

BACKGROUND: Integrin α2β1 inhibitor BTT-3033 (1-(4-fluorophenyl)-N-methyl-N-[4[[(phenylamino)carbonyl]amino]phenyl]-1H-pyrazole-4-sulfonamide) was recently reported to inhibit neurogenic and thromboxane A2-induced human prostate smooth muscle contraction, and thus represents a target with a differen...

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Detalles Bibliográficos
Autores principales: Li, Bingsheng, Li, Pan, Xia, Weiping, You, Baiyang, Yu, Qingfeng, Zhang, Bo, Huang, Ru, Wang, Ruixiao, Liu, Yuhan, Chen, Zhi, Gan, Yu, He, Yao, Hennenberg, Martin, Stief, Christian G., Chen, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506561/
https://www.ncbi.nlm.nih.gov/pubmed/34733932
http://dx.doi.org/10.21037/atm-21-3194