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Selective Integrin Ligands Promote Cell Internalization of the Antineoplastic Agent Fluorouracil

[Image: see text] Drug conjugates consisting of an antineoplastic drug and a targeting receptor ligand could be effective to overcome the heavy side effects of unselective anticancer agents. To address this need, we report here the results of a project aimed to study agonist and antagonist integrin...

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Detalles Bibliográficos
Autores principales: Baiula, Monica, Cirillo, Martina, Martelli, Giulia, Giraldi, Valentina, Gasparini, Elisa, Anelli, Alessandro Claudio, Spampinato, Santi Mario, Giacomini, Daria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506610/
https://www.ncbi.nlm.nih.gov/pubmed/34661072
http://dx.doi.org/10.1021/acsptsci.1c00094