Cargando…

RNA‐binding protein RBM24 represses colorectal tumourigenesis by stabilising PTEN mRNA

BACKGROUND: RNA‐binding motif protein 24 (RBM24) functions as a splicing regulator, which is critical for organ development and is dysregulated in human cancers. Here, we aim to uncover the biological function of RBM24 in colorectal tumourigenesis. METHODS: Xenograft tumour model, Rbm24 knockout and...

Descripción completa

Detalles Bibliográficos
Autores principales: Xia, Rong Mu, Liu, Tao, Li, Wen Gang, Xu, Xiu Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506628/
https://www.ncbi.nlm.nih.gov/pubmed/34709758
http://dx.doi.org/10.1002/ctm2.383