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Thymidylate synthase locus LOH in combination with genotype has prognostic and predictive significance in colorectal cancer

The aim of the current study was to investigate the prognostic and predictive significance of polymorphisms in the thymidylate synthase (TS) gene, alongside the loss of heterozygocity (LOH) at this gene locus in patients with colorectal cancer. Genotyping was carried out for a variable number tandem...

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Detalles Bibliográficos
Autores principales: Kotake, Masanori, Bando, Hiroyuki, Kaneko, Mami, Takemura, Hirofumi, Minamoto, Toshinari, Kawakami, Kazuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506693/
https://www.ncbi.nlm.nih.gov/pubmed/34650802
http://dx.doi.org/10.3892/mco.2021.2398