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ACSL4 contributes to sevoflurane-induced ferroptotic neuronal death in SH-SY5Y cells via the 5' AMP-activated protein kinase/mammalian target of rapamycin pathway

BACKGROUND: Acyl-CoA synthetase long chain family member 4 (ACSL4) has been reported to serve as a major player in the progress of ferroptosis in various diseases. Nevertheless, the functional role and mechanism of ACSL4 in sevoflurane (sev)-induced neuronal death has never been elucidated. METHODS:...

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Detalles Bibliográficos
Autores principales: Cheng, Lei, Zhu, Xiaodan, Liu, Yang, Zhu, Kai, Lin, Kang, Li, Fujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506733/
https://www.ncbi.nlm.nih.gov/pubmed/34734006
http://dx.doi.org/10.21037/atm-21-4249