Cargando…

MicroRNA-146a-5p alleviates lipopolysaccharide-induced NLRP3 inflammasome injury and pro-inflammatory cytokine production via the regulation of TRAF6 and IRAK1 in human umbilical vein endothelial cells (HUVECs)

BACKGROUND: Microribonucleic acids (miRNAs) have an evident role in regulating endothelial inflammation and dysfunction, which characterizes the early stages of atherosclerosis. The NOD-like receptor family pyrin domain-containing protein 3 (NLRP3) inflammasome has been reported to contribute to the...

Descripción completa

Detalles Bibliográficos
Autores principales: Hou, Jingyuan, Deng, Qiaoting, Deng, Xunwei, Zhong, Wei, Liu, Sudong, Zhong, Zhixiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506750/
https://www.ncbi.nlm.nih.gov/pubmed/34733985
http://dx.doi.org/10.21037/atm-21-3903