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MicroRNA-146a-5p alleviates lipopolysaccharide-induced NLRP3 inflammasome injury and pro-inflammatory cytokine production via the regulation of TRAF6 and IRAK1 in human umbilical vein endothelial cells (HUVECs)
BACKGROUND: Microribonucleic acids (miRNAs) have an evident role in regulating endothelial inflammation and dysfunction, which characterizes the early stages of atherosclerosis. The NOD-like receptor family pyrin domain-containing protein 3 (NLRP3) inflammasome has been reported to contribute to the...
Autores principales: | Hou, Jingyuan, Deng, Qiaoting, Deng, Xunwei, Zhong, Wei, Liu, Sudong, Zhong, Zhixiong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506750/ https://www.ncbi.nlm.nih.gov/pubmed/34733985 http://dx.doi.org/10.21037/atm-21-3903 |
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