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Astragaloside IV protects cardiomyocytes against hypoxia injury via HIF-1α and the JAK2/STAT3 pathway

BACKGROUND: Hypoxia is an important cause of myocardial injury due to the heart’s high susceptibility to hypoxia. Astragaloside IV (AS-IV) is the main component of Astragalus membranaceus and could exert cardiac protective role. Here, the effect of AS-IV on hypoxia-injured H9c2 cardiomyocytes was el...

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Detalles Bibliográficos
Autores principales: Li, Bei, Yu, Junjian, Liu, Peipei, Zeng, Taohui, Zeng, Xueliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506767/
https://www.ncbi.nlm.nih.gov/pubmed/34733987
http://dx.doi.org/10.21037/atm-21-4080