Caseinolytic protease P (CLPP) activated by ONC201 inhibits proliferation and promotes apoptosis in human epithelial ovarian cancer cells by inducing mitochondrial dysfunction

BACKGROUND: Caseinolytic protease P (CLPP) is a mitochondrial specific protein which has been reported to be related to tumor cell apoptosis. This study aims to explore the roles of CLPP in human epithelial ovarian cancer (EOC). METHODS: We determined CLPP expression in paracancerous tissues and can...

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Detalles Bibliográficos
Autores principales: Kou, Xinxin, Ding, Hui, Li, Lei, Chao, Hongtu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506775/
https://www.ncbi.nlm.nih.gov/pubmed/34734015
http://dx.doi.org/10.21037/atm-21-4321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506775/
https://www.ncbi.nlm.nih.gov/pubmed/34734015
http://dx.doi.org/10.21037/atm-21-4321

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