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Monensin suppresses cell proliferation and invasion in ovarian cancer by enhancing MEK1 SUMOylation

Ovarian cancer is the most lethal gynecologic malignancy, and is usually diagnosed at an advanced stage. Most patients relapse within 12-24 months and die from progressive chemotherapy-resistant diseases. Significant progress has been made in developing new targeted therapies for human cancer, inclu...

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Detalles Bibliográficos
Autores principales: Yao, Shujuan, Wang, Wen, Zhou, Bin, Cui, Xiujuan, Yang, Hui, Zhang, Shiqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506924/
https://www.ncbi.nlm.nih.gov/pubmed/34650638
http://dx.doi.org/10.3892/etm.2021.10826