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Roflumilast, a type of phosphodiesterase 4 inhibitor, can reduce intestinal injury caused by sepsis

Sepsis is a systemic inflammatory response syndrome caused by infection, which has a complex mechanism. The gastrointestinal tract is commonly the first organ affected by sepsis, but intestinal disease itself can also induce sepsis. Roflumilast has been found to exert anti-inflammatory effects and,...

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Detalles Bibliográficos
Autores principales: Zhang, Zhongyuan, Liang, Meifeng, Wan, Xiongfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506939/
https://www.ncbi.nlm.nih.gov/pubmed/34650646
http://dx.doi.org/10.3892/etm.2021.10834