A computational model of mutual antagonism in the mechano-signaling network of RhoA and nitric oxide

BACKGROUND: RhoA is a master regulator of cytoskeletal contractility, while nitric oxide (NO) is a master regulator of relaxation, e.g., vasodilation. There are multiple forms of cross-talk between the RhoA/ROCK pathway and the eNOS/NO/cGMP pathway, but previous work has not studied their interplay...

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Detalles Bibliográficos
Autores principales: Surendran, Akila, Forbes Dewey, C., Low, Boon Chuan, Tucker-Kellogg, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507106/
https://www.ncbi.nlm.nih.gov/pubmed/34635055
http://dx.doi.org/10.1186/s12860-021-00383-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507106/
https://www.ncbi.nlm.nih.gov/pubmed/34635055
http://dx.doi.org/10.1186/s12860-021-00383-5

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