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Effects of early geometric confinement on the transcriptomic profile of human cerebral organoids

BACKGROUND: Human cerebral organoids (hCO) are attractive systems due to their ability to model important brain regions and transcriptomics of early in vivo brain development. To date, they have been used to understand the effects of genetics and soluble factors on neurodevelopment. Interestingly, o...

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Detalles Bibliográficos
Autores principales: Sen, Dilara, Voulgaropoulos, Alexis, Keung, Albert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507123/
https://www.ncbi.nlm.nih.gov/pubmed/34641840
http://dx.doi.org/10.1186/s12896-021-00718-2