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Bisperoxovanadium promotes motor neuron survival and neuromuscular innervation in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is the most common motor neuron (MN) disease, with no present cure. The progressive loss of MNs is the hallmark of ALS. We have previously shown the therapeutic effects of the phosphatase and tensin homolog (PTEN) inhibitor, potassium bisperoxo (picolinato) vanadi...

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Detalles Bibliográficos
Autores principales: Wang, Junmei, Tierney, Lydia, Mann, Ranjeet, Lonsway, Thomas, Walker, Chandler L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507234/
https://www.ncbi.nlm.nih.gov/pubmed/34635126
http://dx.doi.org/10.1186/s13041-021-00867-7