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Recovery of strain-resolved genomes from human microbiome through an integration framework of single-cell genomics and metagenomics
BACKGROUND: Obtaining high-quality (HQ) reference genomes from microbial communities is crucial for understanding the phylogeny and function of uncultured microbes in complex microbial ecosystems. Despite improvements in bioinformatic approaches to generate curated metagenome-assembled genomes (MAGs...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507239/ https://www.ncbi.nlm.nih.gov/pubmed/34641955 http://dx.doi.org/10.1186/s40168-021-01152-4 |