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Dulaglutide improves muscle function by attenuating inflammation through OPA-1-TLR-9 signaling in aged mice

Dulaglutide, a glucagon-like peptide-1 receptor (GLP-1R) agonist, is widely used to treat diabetes. However, its effects on muscle wasting due to aging are poorly understood. In the current study, we investigated the therapeutic potential and underlying mechanism of dulaglutide in muscle wasting in...

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Detalles Bibliográficos
Autores principales: Khin, Phyu Phyu, Hong, Yeonhee, Yeon, MyeongHoon, Lee, Dae Ho, Lee, Jong Han, Jun, Hee-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507261/
https://www.ncbi.nlm.nih.gov/pubmed/34537761
http://dx.doi.org/10.18632/aging.203546