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Breed-specific reference sequence optimized mapping accuracy of NGS analyses for pigs

BACKGROUND: Reference sequences play a vital role in next-generation sequencing (NGS), impacting mapping quality during genome analyses. However, reference genomes usually do not represent the full range of genetic diversity of a species as a result of geographical divergence and independent demogra...

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Detalles Bibliográficos
Autores principales: Wang, Dan, Yang, Liu, Ning, Chao, Liu, Jian-Feng, Zhao, Xingbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507312/
https://www.ncbi.nlm.nih.gov/pubmed/34641784
http://dx.doi.org/10.1186/s12864-021-08030-1