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Breed-specific reference sequence optimized mapping accuracy of NGS analyses for pigs
BACKGROUND: Reference sequences play a vital role in next-generation sequencing (NGS), impacting mapping quality during genome analyses. However, reference genomes usually do not represent the full range of genetic diversity of a species as a result of geographical divergence and independent demogra...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507312/ https://www.ncbi.nlm.nih.gov/pubmed/34641784 http://dx.doi.org/10.1186/s12864-021-08030-1 |