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Dynamic Interplay between Lower-Grade Glioma Instability and Brain Metaplasticity: Proposal of an Original Model to Guide the Therapeutic Strategy
SIMPLE SUMMARY: The behavior of diffuse lower-grade glioma (LGG) is changing over time, spontaneously, and in reaction to therapies. Due to genomic instability and clonal expansion, although LGG initially progresses slowly, the growth accelerates at the time of malignant transformation. Furthermore,...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507523/ https://www.ncbi.nlm.nih.gov/pubmed/34638248 http://dx.doi.org/10.3390/cancers13194759 |