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Fibroblasts Influence Metastatic Melanoma Cell Sensitivity to Combined BRAF and MEK Inhibition

SIMPLE SUMMARY: Preclinical 3D in vitro coculture models are known to be more complex systems than monolayer cell culture and mimic the physiological environment more closely. Three-dimensional dermal equivalents provide a relevant environment for cutaneous metastatic melanoma cells and are capable...

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Detalles Bibliográficos
Autores principales: Morales, Delphine, Vigneron, Pascale, Ferreira, Ines, Hamitou, Warda, Magnano, Mikael, Mahenthiran, Laxsika, Lok, Catherine, Vayssade, Muriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507536/
https://www.ncbi.nlm.nih.gov/pubmed/34638245
http://dx.doi.org/10.3390/cancers13194761