Defining the Role of GLI/Hedgehog Signaling in Chemoresistance: Implications in Therapeutic Approaches

SIMPLE SUMMARY: Chemotherapy is the mainstay of cancer treatment; however, its use is limited due to the emergence of chemotherapeutic drug resistance in cancers. An essential developmental pathway, namely Hedgehog (Hh), has recently emerged as a major modulator of cancer progression and, more impor...

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Detalles Bibliográficos
Autores principales: Chai, Jian Yi, Sugumar, Vaisnevee, Alshanon, Ahmed F., Wong, Won Fen, Fung, Shin Yee, Looi, Chung Yeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507559/
https://www.ncbi.nlm.nih.gov/pubmed/34638233
http://dx.doi.org/10.3390/cancers13194746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507559/
https://www.ncbi.nlm.nih.gov/pubmed/34638233
http://dx.doi.org/10.3390/cancers13194746

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