Imaging-Guided Evaluation of the Novel Small-Molecule Benzosuberene Tubulin-Binding Agent KGP265 as a Potential Therapeutic Agent for Cancer Treatment

SIMPLE SUMMARY: Vascular-disrupting agents promise significant therapeutic efficacy against solid tumors by selectively damaging tumor-associated vasculature. Dynamic BLI and oxygen-enhanced multispectral optoacoustic tomography (OE-MSOT) were used to compare vascular shutdown following administrati...

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Detalles Bibliográficos
Autores principales: Guo, Yihang, Wang, Honghong, Gerberich, Jeni L., Odutola, Samuel O., Charlton-Sevcik, Amanda K., Li, Maoping, Tanpure, Rajendra P., Tidmore, Justin K., Trawick, Mary Lynn, Pinney, Kevin G., Mason, Ralph P., Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507561/
https://www.ncbi.nlm.nih.gov/pubmed/34638255
http://dx.doi.org/10.3390/cancers13194769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507561/
https://www.ncbi.nlm.nih.gov/pubmed/34638255
http://dx.doi.org/10.3390/cancers13194769

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