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Implications of Intratumor Heterogeneity on Consensus Molecular Subtype (CMS) in Colorectal Cancer

SIMPLE SUMMARY: Colorectal cancer (CRC) has been divided into four consensus molecular subtypes (CMS) using the unsupervised clustering of bulk transcriptomic data. The CMS, which align with known biological differences in CRC, have helped address inter-tumor heterogeneity and have been shown to be...

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Detalles Bibliográficos
Autores principales: Chowdhury, Saikat, Hofree, Matan, Lin, Kangyu, Maru, Dipen, Kopetz, Scott, Shen, John Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507736/
https://www.ncbi.nlm.nih.gov/pubmed/34638407
http://dx.doi.org/10.3390/cancers13194923