ACKR4 in Tumor Cells Regulates Dendritic Cell Migration to Tumor-Draining Lymph Nodes and T-Cell Priming

SIMPLE SUMMARY: Our study demonstrated that Atypical Chemokine Receptor 4 (ACKR4) was downregulated in human colorectal cancer (CRC) compared with normal colon tissues. Loss of ACKR4 in human CRC was associated with a weak anti-tumor immune response. Knockdown of ACKR4 in tumor cells impairs the den...

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Detalles Bibliográficos
Autores principales: Wangmo, Dechen, Premsrirut, Prem K., Yuan, Ce, Morris, William S., Zhao, Xianda, Subramanian, Subbaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507805/
https://www.ncbi.nlm.nih.gov/pubmed/34638505
http://dx.doi.org/10.3390/cancers13195021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507805/
https://www.ncbi.nlm.nih.gov/pubmed/34638505
http://dx.doi.org/10.3390/cancers13195021

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