TIMP1 and TIMP2 Downregulate TGFβ Induced Decidual-like Phenotype in Natural Killer Cells

SIMPLE SUMMARY: Cancer patients are characterized by NK cells with altered surface markers, such as CD56 brightness, CD9, CD49a (pro-angiogenic) and PD-1, and TIM-3 (exhaustion), that favor immune escape. Transforming growth factor-beta (TGFβ) is a major tumor-derived cytokine that favors cancer gro...

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Detalles Bibliográficos
Autores principales: Albini, Adriana, Gallazzi, Matteo, Palano, Maria Teresa, Carlini, Valentina, Ricotta, Riccardo, Bruno, Antonino, Stetler-Stevenson, William G., Noonan, Douglas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507839/
https://www.ncbi.nlm.nih.gov/pubmed/34638439
http://dx.doi.org/10.3390/cancers13194955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507839/
https://www.ncbi.nlm.nih.gov/pubmed/34638439
http://dx.doi.org/10.3390/cancers13194955

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