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Differential MMP-14 Targeting by Lumican-Derived Peptides Unraveled by In Silico Approach

SIMPLE SUMMARY: This work aimed to investigate the interactions of lumican-derived peptides and MMP-14. An in silico approach unraveled key residues in the amino acid sequence of MMP-14 interacting with the Small Leucine-Rich Proteoglycan (SLRP) lumican-derived peptides. The in silico docking analys...

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Detalles Bibliográficos
Autores principales: Dauvé, Jonathan, Belloy, Nicolas, Rivet, Romain, Etique, Nicolas, Nizet, Pierre, Pietraszek-Gremplewicz, Katarzyna, Karamanou, Konstantina, Dauchez, Manuel, Ramont, Laurent, Brézillon, Stéphane, Baud, Stéphanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507859/
https://www.ncbi.nlm.nih.gov/pubmed/34638415
http://dx.doi.org/10.3390/cancers13194930