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Molecular Mechanism of EGFR-TKI Resistance in EGFR-Mutated Non-Small Cell Lung Cancer: Application to Biological Diagnostic and Monitoring

SIMPLE SUMMARY: Non-small cell lung cancer (NSCLC) is the most common cancer in the world. For common EGFR mutations, treatment is based on different inhibitors. Despite the excellent disease control with inhibitors, acquired resistance inevitably occurs and remains a biological challenge. This lead...

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Detalles Bibliográficos
Autores principales: Reita, Damien, Pabst, Lucile, Pencreach, Erwan, Guérin, Eric, Dano, Laurent, Rimelen, Valérie, Voegeli, Anne-Claire, Vallat, Laurent, Mascaux, Céline, Beau-Faller, Michèle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507869/
https://www.ncbi.nlm.nih.gov/pubmed/34638411
http://dx.doi.org/10.3390/cancers13194926