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Endometrial PTEN Deficiency Leads to SMAD2/3 Nuclear Translocation

SIMPLE SUMMARY: PTEN is a protein highly altered in endometrial cancer. PTEN mutation or deficiency leads to the activation of other downstream proteins that are important to the development of cancers. In this study, we have identified the SMAD2/3 proteins as targets of PTEN deficiency. We have fou...

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Detalles Bibliográficos
Autores principales: Eritja, Núria, Navaridas, Raúl, Ruiz-Mitjana, Anna, Vidal-Sabanés, Maria, Egea, Joaquim, Encinas, Mario, Matias-Guiu, Xavier, Dolcet, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507901/
https://www.ncbi.nlm.nih.gov/pubmed/34638474
http://dx.doi.org/10.3390/cancers13194990