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Expression Patterns of TOP2A and SIRT1 Are Predictive of Survival in Patients with High-Risk Soft Tissue Sarcomas Treated with a Neoadjuvant Anthracycline-Based Chemotherapy

SIMPLE SUMMARY: High-risk soft tissue sarcomas (HR-STS) account for less than 1% of all malignancies in adults. Despite optimal local treatment, almost half of patients will die within five years of their diagnosis. Chemoresistance is a major responsible mechanism for treatment failure in advanced t...

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Detalles Bibliográficos
Autores principales: Berclaz, Luc M., Altendorf-Hofmann, Annelore, Dürr, Hans Roland, Klein, Alexander, Angele, Martin K., Albertsmeier, Markus, Schmidt-Hegemann, Nina-Sophie, Di Gioia, Dorit, Knösel, Thomas, Lindner, Lars H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507907/
https://www.ncbi.nlm.nih.gov/pubmed/34638362
http://dx.doi.org/10.3390/cancers13194877