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Expression Patterns of TOP2A and SIRT1 Are Predictive of Survival in Patients with High-Risk Soft Tissue Sarcomas Treated with a Neoadjuvant Anthracycline-Based Chemotherapy
SIMPLE SUMMARY: High-risk soft tissue sarcomas (HR-STS) account for less than 1% of all malignancies in adults. Despite optimal local treatment, almost half of patients will die within five years of their diagnosis. Chemoresistance is a major responsible mechanism for treatment failure in advanced t...
Autores principales: | Berclaz, Luc M., Altendorf-Hofmann, Annelore, Dürr, Hans Roland, Klein, Alexander, Angele, Martin K., Albertsmeier, Markus, Schmidt-Hegemann, Nina-Sophie, Di Gioia, Dorit, Knösel, Thomas, Lindner, Lars H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507907/ https://www.ncbi.nlm.nih.gov/pubmed/34638362 http://dx.doi.org/10.3390/cancers13194877 |
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