UBE2M Drives Hepatocellular Cancer Progression as a p53 Negative Regulator by Binding to MDM2 and Ribosomal Protein L11

SIMPLE SUMMARY: Herein, the oncogenic role of UBE2M as an E2 NEDD8-conjugating enzyme was explored in hepatocellular carcinoma (HCC) cells, since neddylation plays a critical role in tumorigenesis. To address this issue, human tissue array and TCGA analysis were conducted in HCCs to find overexpress...

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Detalles Bibliográficos
Autores principales: Kim, Ju-Ha, Jung, Ji Hoon, Lee, Hyo-Jung, Sim, Deok-Yong, Im, Eunji, Park, Jieon, Park, Woon-Yi, Ahn, Chi-Hoon, Shim, Bum-Sang, Kim, Bonglee, Kim, Sung-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507934/
https://www.ncbi.nlm.nih.gov/pubmed/34638383
http://dx.doi.org/10.3390/cancers13194901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507934/
https://www.ncbi.nlm.nih.gov/pubmed/34638383
http://dx.doi.org/10.3390/cancers13194901

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