Targeting Nanomaterials to Head and Neck Cancer Cells Using a Fragment of the Shiga Toxin as a Potent Natural Ligand

SIMPLE SUMMARY: To mimic natural ligand-specific cell entry mechanisms, we have reproduced the molecular cues found in the Shiga toxin to target nanomaterials into head and neck cancer (HNC) cells bearing the globotriaosylceramide receptor (known as GB3 or CD77). This is a globoside typically found...

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Detalles Bibliográficos
Autores principales: Navarro-Palomares, Elena, García-Hevia, Lorena, Padín-González, Esperanza, Bañobre-López, Manuel, Villegas, Juan C., Valiente, Rafael, Fanarraga, Mónica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507991/
https://www.ncbi.nlm.nih.gov/pubmed/34638405
http://dx.doi.org/10.3390/cancers13194920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507991/
https://www.ncbi.nlm.nih.gov/pubmed/34638405
http://dx.doi.org/10.3390/cancers13194920

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