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Targeting Nanomaterials to Head and Neck Cancer Cells Using a Fragment of the Shiga Toxin as a Potent Natural Ligand
SIMPLE SUMMARY: To mimic natural ligand-specific cell entry mechanisms, we have reproduced the molecular cues found in the Shiga toxin to target nanomaterials into head and neck cancer (HNC) cells bearing the globotriaosylceramide receptor (known as GB3 or CD77). This is a globoside typically found...
Autores principales: | Navarro-Palomares, Elena, García-Hevia, Lorena, Padín-González, Esperanza, Bañobre-López, Manuel, Villegas, Juan C., Valiente, Rafael, Fanarraga, Mónica L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507991/ https://www.ncbi.nlm.nih.gov/pubmed/34638405 http://dx.doi.org/10.3390/cancers13194920 |
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