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Novel 3D µtissues Mimicking the Fibrotic Stroma in Pancreatic Cancer to Study Cellular Interactions and Stroma-Modulating Therapeutics

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) is the most prevalent and aggressive type of pancreatic cancer with a low 5-year survival rate of only 8%. The cellular arrangement plays a crucial role in PDAC, which is characterized by a highly fibrotic environment around the tumor cells, pr...

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Detalles Bibliográficos
Autores principales: Pednekar, Kunal P., Heinrich, Marcel A., van Baarlen, Joop, Prakash, Jai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508009/
https://www.ncbi.nlm.nih.gov/pubmed/34638490
http://dx.doi.org/10.3390/cancers13195006