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Novel 3D µtissues Mimicking the Fibrotic Stroma in Pancreatic Cancer to Study Cellular Interactions and Stroma-Modulating Therapeutics
SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) is the most prevalent and aggressive type of pancreatic cancer with a low 5-year survival rate of only 8%. The cellular arrangement plays a crucial role in PDAC, which is characterized by a highly fibrotic environment around the tumor cells, pr...
Autores principales: | Pednekar, Kunal P., Heinrich, Marcel A., van Baarlen, Joop, Prakash, Jai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508009/ https://www.ncbi.nlm.nih.gov/pubmed/34638490 http://dx.doi.org/10.3390/cancers13195006 |
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