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Comparing the Effect of Multiple Histone Deacetylase Inhibitors on SSTR2 Expression and [(111)In]In-DOTATATE Uptake in NET Cells

SIMPLE SUMMARY: Patients diagnosed with neuroendocrine tumors (NETs) are often treated with peptide receptor radionuclide therapy (PRRT). This therapy targets the somatostatin type-2 receptors (SSTR2) frequently overexpressed on these types of tumors. Although this therapy has proven to be effective...

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Detalles Bibliográficos
Autores principales: Klomp, Maria J., Dalm, Simone U., van Koetsveld, Peter M., Dogan, Fadime, de Jong, Marion, Hofland, Leo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508045/
https://www.ncbi.nlm.nih.gov/pubmed/34638389
http://dx.doi.org/10.3390/cancers13194905