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Low Levels of TRIM28-Interacting KRAB-ZNF Genes Associate with Cancer Stemness and Predict Poor Prognosis of Kidney Renal Clear Cell Carcinoma Patients

SIMPLE SUMMARY: This is the first report investigating the involvement of TRIM28-interacting KRAB-ZNFs in kidney cancer progression. We demonstrate a significant negative association between KRAB-ZNFs and cancer stemness followed by an attenuated immune-suppressive response and reveal the prognostic...

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Detalles Bibliográficos
Autores principales: Czerwinska, Patrycja, Mackiewicz, Andrzej Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508054/
https://www.ncbi.nlm.nih.gov/pubmed/34638319
http://dx.doi.org/10.3390/cancers13194835