Cargando…
Low Levels of TRIM28-Interacting KRAB-ZNF Genes Associate with Cancer Stemness and Predict Poor Prognosis of Kidney Renal Clear Cell Carcinoma Patients
SIMPLE SUMMARY: This is the first report investigating the involvement of TRIM28-interacting KRAB-ZNFs in kidney cancer progression. We demonstrate a significant negative association between KRAB-ZNFs and cancer stemness followed by an attenuated immune-suppressive response and reveal the prognostic...
Autores principales: | Czerwinska, Patrycja, Mackiewicz, Andrzej Adam |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508054/ https://www.ncbi.nlm.nih.gov/pubmed/34638319 http://dx.doi.org/10.3390/cancers13194835 |
Ejemplares similares
-
Melanoma Stem Cell-Like Phenotype and Significant Suppression of Immune Response within a Tumor Are Regulated by TRIM28 Protein
por: Czerwinska, Patrycja, et al.
Publicado: (2020) -
Mapping the interaction between Trim28 and the KRAB domain at the center of Trim28 silencing of endogenous retroviruses
por: Taka, Jamie R. H., et al.
Publicado: (2022) -
The expression signature of cancer‐associated KRAB‐ZNF factors identified in TCGA pan‐cancer transcriptomic data
por: Machnik, Marta, et al.
Publicado: (2019) -
The role of TRIM family proteins in the regulation of cancer stem cell self‐renewal
por: Jaworska, Anna Maria, et al.
Publicado: (2019) -
The complexity of TRIM28 contribution to cancer
por: Czerwińska, Patrycja, et al.
Publicado: (2017)